• br Acknowledgments br Significance The mechanisms underlying

  2019-09-12

  Significance The mechanisms underlying the adverse effects of Epo-stimulating agents on the reduced survival of cancer patients are not well understood.

• br Conclusions and future perspectives

  2019-09-11

  Conclusions and future perspectives It is now evident that selective ETA or nonselective endothelin receptor antagonism provides therapeutic potentials against a variety of cardiovascular diseases such as hypertension, PAH, and diabetic microvascular dysfunction (Fig. 1).

• Gap 26 br Discussion The N terminal domain of

  2019-09-10

  Discussion The N-terminal domain of DDRs has long been recognized as a member of the DS superfamily (Johnson et al., 1993, Karn et al., 1993), and its role in collagen binding is understood in atomic detail (Carafoli et al., 2009, Ichikawa et al., 2007).

• br Overall system architecture In

  2019-09-09

  Overall system architecture In this Rosiglitazone section we provide a description of the system under study, and its surrounding environment, on an “as is” basis.

• There are numerous theories of schizophrenia etiopathology a

  2019-09-07

  There are numerous theories of schizophrenia etiopathology and genetics is often taken into consideration [25].

• Further studies are needed as continuation of this work to

  2019-09-06

  Further studies are needed as continuation of this work to explore the effects of type and position of substituents of pyridazinone ring on anti-inflammatory activity profile.

• br DDR mediated signaling DDRs initiate signaling pathways

  2019-09-05

  DDR-mediated signaling DDRs initiate signaling pathways in a context and cell type-dependent manner.

• There are studies that evaluated the

  2019-09-04

  There are studies that evaluated the stability of CMV DNA over different periods of time. A study that evaluated stability of EDTA plasma samples stored over a 21-day period at 4 °C found no significant change in the viral loads or any trend of continued DNA degradation [9].

• PSI-6206 Enolase is an example of a

  2019-09-03

  Enolase is an example of a moonlighting protein that displays multiple biological actions, including plasminogen, laminin, fibronectin, mucin and cytokeratin binding properties.

• Three dimensional conformational changes in the cargo

  2019-09-02

  Three-dimensional conformational changes in the cargo protein’s NES, caused by protein phosphorylation, dephosphorylation, or mutation, can regulate CRM1 binding (Craig et al., 2002, Vogt et al., 2005).

• The inhibition of FAS by C produces

  2019-08-30

  The inhibition of FAS by C75 produces an accumulation of malonyl-CoA which is difficult to reconcile with the activation of CPT1 reported by others [2], [16], [17], [18].

• Among the Ub interactions observed in

  2019-08-29

  Among the ~Ub interactions observed in the HOIP structure is one that involves a RING2 domain (from the non-cognate HOIP) [47].

• This research was funded by grants

  2019-08-28

  This research was funded by grants from the National Institute on Aging (2R01AG017141-06A2) and the National Center for Complementary and Alternative Medicine (P01AT002034).

• Despite the important agronomic traits

  2019-08-27

  Despite the important agronomic traits regulated by SUMO, most research studies on SUMOylation have been mainly limited to model plants

• Partial suppression of the cot ts phenotype by deletion of

  2019-08-26

  Partial suppression of the cot-1 (ts) phenotype by deletion of gul-1 has been well documented (Seiler et al., 2006).

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