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br Acknowledgement AM and SK
2019-11-08
Acknowledgement AM and SK thank ICMR, New Delhi, India for the financial assistance BIC/12(32)/2012. SK is the recipient of JRF from the project. RK and GJ thank Bristol-Myer Squibb (Grant # 34003085), USA for financial support. Introduction Proliferating Cell Nuclear Antigen (PCNA) is a high
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Magnetic interactions between metal ions are usually describ
2019-11-08
Magnetic interactions between metal ions are usually described by superexchange via intermediate ligands. Although the general principles of the superexchange mechanism are essentially the same for d and f ions, calculations of exchange parameters for lanthanides are more difficult than for transiti
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The mechanism underlying the increased
2019-11-08
The mechanism underlying the increased PON1 levels found in greenhouse workers may be accounted for by an increased protein Ranolazine following pesticide interaction with different nuclear receptors as also occurs with other chemicals, such as polyphenols and statins [28]. A number of nuclear rece
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In the intestine absorbed cholesterol can either be
2019-11-08
In the intestine, absorbed cholesterol can either be esterified by ACAT2 (Soat2) and packed into chylomicrons, transported back to the intestinal lumen by ABCG5/ABCG8, or it can be transported into HDL by ABCA1. ACAT2 is confined to enterocytes and hepatocytes and esterifies cholesterol for intrace
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br Funding This work was supported by the Natural Science
2019-11-08
Funding This work was supported by the Natural Science Foundations of China (81072327 and 81273114), Research Fund for the Doctoral Program of Higher Education of China (20103234110005), Key Program of Educational Commission of Jiangsu Province of China (11KJA330002), and a Project Funded by the
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Hinokitiol has versatile abilities as anticancer antimicrobi
2019-11-08
Hinokitiol has versatile abilities as anticancer, antimicrobial and molecule transport agents and appears to have no developmental toxicity or carcinogenic effects (Imai et al., 2006b). For anticancer activities, it causes apoptosis and Phosphoramidon Disodium Salt arrest in many different types of
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br Methods br Results Our study
2019-11-07
Methods Results Our study focused on consecutive postural adjustments (CPAs) between IS and BS (the shaded areas on Fig. 2); that is to say, the Rx kinetics that occur after the end of an upper limb movement. It was dedicated to examining the main features of CPAs and the influence of movement
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The aim of the following work was to
2019-11-07
The aim of the following work was to untap the potential of DIS as a low-cost substrate for fungal production of lignocellulolytic enzymes via SSF. Fungal strains with the ability to transform the unpretreated DIS to a mixture of industrially relevant lignocellulases were identified. Furthermore, th
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Dysfunction of the ubiquitin proteasome system causes
2019-11-07
Dysfunction of the ubiquitin-proteasome system causes abnormal organelle morphology and impairs sperm formation and maturation steps resulting in male infertility [[7], [8], [9]]; this indicates that ubiquitination is essential for spermatogenesis and sperm function during fertilization. β-catenin i
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Electron transport via DHODH activity
2019-11-07
Electron transport via DHODH activity will allow the generation of mitochondrial ROS without the consumption of α-ketoglutarate or NADH. Glutamine-dependent flux through the TCA cycle and oxidative phosphorylation can also enable generation of mitochondrial ROS (Weinberg et al., 2010). The latter pr
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Hinokitiol has versatile abilities as
2019-11-07
Hinokitiol has versatile abilities as anticancer, antimicrobial and molecule transport agents and appears to have no developmental toxicity or carcinogenic effects (Imai et al., 2006b). For anticancer activities, it causes apoptosis and mavacamten arrest in many different types of cancers, such as
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MSCs are self renewing multipotent
2019-11-07
MSCs are self-renewing, multipotent progenitor cells, with multilineage potential to differentiate into adipocytes, osteocytes, and chondrocytes. In addition, MSCs can migrate to sites of inflammation, supporting hematopoiesis and homeostatic maintenance. Given their unique therapeutic properties, M
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Evodiamine br Materials and methods br
2019-11-07
Materials and methods Results Discussion PKA and Epac are two principal effector proteins involved in cAMP signaling; they are expressed in a wide range of tissues and control diverse biological functions [10]. The existence of two cAMP effectors provides more precise regulation of cAMP sig
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Nitric oxide synthase NOS is a predominant enzyme of
2019-11-07
Nitric oxide synthase (NOS) is a predominant enzyme of immune system, which elaborates nitric oxide (NO) from the amino 7441 arginine (Arg). NO mediates vasodilatation, blood pressure regulation, neurotransmission, host defense, and macrophage-mediated immunity, among an array of other functions (V
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br Materials and methods br
2019-11-06
Materials and methods Results Discussion In this study we characterized in more detail the interrelationship between the expression levels of the B. malayi Bm-cpl-3 and Bm-cpl-6 cysteine proteases and the fitness of Wolbachia, and consequently that of the parasite. Our present in vitro data
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