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Enzyme selectivity of many enzymes like galactosidases acyla
2020-05-11

Enzyme selectivity of many Puromycin aminonucleoside like β-galactosidases, acylases, epoxyhydrolases, lipases, etc. has also been modulated by using different immobilization techniques. It can result in the selection of optimal biocatalyst for different processes. This has many advantages over str
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Polymorphism of the CD gene also affected the
2020-05-09

Polymorphism of the CD226 gene also affected the progression rate without any significant effect on autoantibody formation. This gene has been reported to be a common genetic factor in multiple autoimmune diseases such as SLE, systemic sclerosis and type 1 diabetes [43]. CD226 is an immunoglobulin s
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We found that the postnatal absence of
2020-05-09

We found that the postnatal absence of norepinephrine yields differing effects depending on noradrenergic receptor type and PF-573228 receptor region. The density of α1-AR, indicated by [3H]prazosin binding was similar between Dbh+/− and Dbh−/− mice except for a significant increase in hippocampus
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The DNA damage response DDR is
2020-05-09

The DNA damage response (DDR) is a cellular mechanism that protects against DNA damage induced by endogenous and exogenous factors, it includes changes in cellular processes such as Cy5 Firefly Luciferase mRNA receptor regulation, DNA damage repair, apoptosis and chromatin remodeling. In recent year
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It is well known that
2020-05-09

It is well known that, nanostructured transition metal oxides are the most promising candidates as electrode for pseudocapacitors due to their attractive properties such as environmentally friendly, high theoretical capacitance, low cost and easily abundant [15], [16]. Numerous investigations have b
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If the unwanted objects detected
2020-05-09

If the unwanted objects detected by OpenComet are manually deleted, and then the DNA (%) in tail is computed, the performance of the present method can be compared more effectively. Therefore, performance of OpenComet is analysed in two ways as Approach 1 and Approach 2. Approach 1, considers the DN
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In contrast to the methylation that is catalyzed
2020-05-09

In contrast to the methylation that is catalyzed exclusively by DNMTs, there have been suggested several pathways that could induce demethylation (Watt & Molloy, 1988). However, the existence and influencing of enzymes that promote active demethylation remains elusive. Studies aiming to gain more in
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br Competing interests br Acknowledgements br
2020-05-09

Competing interests Acknowledgements Introduction Diacylglycerol kinase (DGK) phosphorylates diacylglycerol (DG) in biomembranes to produce phosphatidic ZM 447439 synthesis (PA) [1], [2], [3], [4], [5], [6]. To date, ten mammalian DGK isozymes (α, β, γ, δ, ε, ζ, η, θ, ι and κ) have been id
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Funding sources This study was funded by European Community
2020-05-09

Funding sources This study was funded by European Community’s Seventh Framework Programme under grant agreement No. 305662 (Project: Community-based scheduled screening and treatment of malaria in pregnancy for improved maternal and infant health: a cluster-randomized trial ‘COSMIC’). Acknowledg
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In the case of ionic liquids the association scheme should
2020-05-09

In the case of ionic liquids, the association scheme should be determined and considered for calculations. H. Soltani Panah (2017) suggested the 2B scheme for the imidazolium-based ionic liquids. His speculation has been used in this study for the modeling [22]. Considering 2B association scheme, th
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Table gives the list of components
2020-05-09

Table 1 gives the list of components which will be modeled. Transient Voltage Suppressor (TVS) as well as passive elements will be also modeled. For each component, we will choose the EMC (emission and immunity) and transient immunity measurement method adapted to extract the component model. A com
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br Disclosure and conflicts of interest br Acknowledgements
2020-05-09

Disclosure and conflicts of interest Acknowledgements This research was supported by grant (BT/PR/11293/BRB/10/849/2008) from Department of Biotechnology (DBT), Government of India and a DST YOS Chair Professorship to PB. The mass spectrometry facility is supported by an institutional program
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In contrast irinotecan has shown much less myelosuppression
2020-05-08

In contrast, irinotecan has shown much less myelosuppression and may be more active in Ewing sarcoma both alone and in combination with temozolamide. One phase II study of 13 heavily pretreated Ewing sarcoma patients demonstrated a response rate of 38% including 2 complete responses (Bisogno et al.,
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The ERR gene lacks the typical TATA and
2020-05-08

The ERRα gene lacks the typical TATA and CAAT boxes, but has multiple consensus Sp1 binding elements in the GC-rich promoter (Shi et al., 1997). Previously, our laboratory has shown that ERRα expression is upregulated in the mouse uterus by estrogen (Shigeta et al., 1997) and recently we identified
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Taken together this study gives first insights into the
2020-05-08

Taken together, this study gives first insights into the complex effect of DNMT inhibition on pattern separation. Acute administration of RG108 enhanced pattern separation performance measured with the OPS task and increased Bdnf1 expression. However, this effect was only acute, and was not present
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