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A genomic DNA sequence was retrieved Scaffold from
2020-08-05
A genomic DNA sequence was retrieved (Scaffold_30) from the fugu genomic database ( v3.0), which encodes the homolog of CXCL8 of many other vertebrates and specific primers CXCL8F1 and CXCL8R1 () were designed for 3′-RACE and 5′-RACE PCR, respectively. First-strand thymus cDNA was used as template.
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In this study we systematically investigated the anti cancer
2020-08-05
In this study, we systematically investigated the anti-cancer activity of AT7519 focusing on its in vitro as well as in vivo effects on chemoresistant cervical and colon cancer cells. Using multiple cell lines and xenograft mouse models, we demonstrate that AT7519 is a promising candidate to overcom
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Since corticotropin releasing factor CRF was isolated and ch
2020-08-05
Since corticotropin-releasing factor (CRF) was isolated and characterized as the major physiological regulator of the hypothalamus-pituitary-adrenal gland axis and was shown to be responsible for the coordination of the endocrine, autonomic and behavioral responses associated with stress (Vale et al
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br Characteristics of the HT regimen with
2020-08-05
Characteristics of the HT regimen with respect to the progestogen and breast cancer risk Conclusions Contributors and their role Competing interest Funding Provenance and peer review Introduction Schwann TAK-715 are the myelinating cells of the peripheral nervous system. After d
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Ticarcillin sodium australia Proteolysis by CPs is crucially
2020-08-04
Proteolysis by CPs is crucially important for cereal seed development and germination. However, these enzymes must be tightly controlled. Pre-harvest sprouting is a phenomenon in which the control of CPs is disrupted. This disruption manifests in the premature synthesis and activation of CPs, leadin
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br Results br Discussion Nuclear
2020-08-04
Results Discussion Nuclear export of vRNP was originally thought to be mediated by the NEP/CRM1 interaction (O\'Neill et al., 1998), but several later studies indicated a role for NP in vRNP nuclear export: for example, LMB inhibits nuclear export of vRNP in a NEP-independent manner (Elton et
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In various thermal recovery processes of heavy
2020-08-04
In various thermal recovery processes of heavy reverse transcriptase inhibitors and bitumens, e.g., Steam Assisted Gravity Drainage (SAGD) and Cyclic Steam Stimulation (CSS), hydrocarbons are produced by heating reservoir formations with a hot heat-carrying fluid such as water. Increasing temperatur
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Our module is designed to allow in process
2020-08-04
Our module is designed to allow in-process measurement of [C]-tracer molar activity (MA, GBq/μmol at EOB) using a Apoptozole detector with a UV detector at the outlet of the HPLC-portion of the system. In the HPLC chromatogram, peak analysis of the chromatographic data utilized PeakSimple software (
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br Conclusion br Conflicts of interest br Acknowledgements T
2020-08-04
Conclusion Conflicts of interest Acknowledgements This study was financially supported by The Science and Engineering Research Board (SERB), Department of Science & Technology (DST), Government of India under the Fast Track Scheme for Young Scientist to Dr. V. Dhananjayan (No: SB/FT/LS-140/
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There is a considerable molecular genetic heterogeneity
2020-08-04
There is a considerable molecular genetic heterogeneity within ES/PNET. As mentioned above, either or can rearrange with in these gene fusions. Furthermore, for either gene fusion, additional heterogeneity stems from the location of the genomic breakpoints of the translocation, resulting in diffe
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The CoA IT sequence is presently unknown making it one
2020-08-04
The CoA-IT sequence is presently unknown, making it one of the 1078 orphan enzymes currently listed in the ORENZA database (EC 2.3.2.147) [188]. Thus, presently the only way to study of CoA-IT is by measuring its enzyme activity or by pharmacological means [57,[189], [190], [191], [192]]. The import
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Rheumatoid arthritis manifests in the joints
2020-08-04
Rheumatoid arthritis manifests in the joints both as synovitis, i.e. the growth of the synovial lining layer, and as joint swelling with exudates in the synovial joint space. We retrieved most of the data on synovial fluid, the edema of inflamed joints, but also had the possibility to assess inflame
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At first cartilage damage in osteoarthritis reflects the los
2020-08-04
At first, cartilage damage in osteoarthritis reflects the loss of proteoglycan and collagen network that increases the swelling of tissues. The incremented expression of DDR2 receptor has also co-related with the depletion of cartilage in surgically induced OA model [8]. Osteoarthritis, a degenerati
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From our mutational studies we found that both
2020-08-04
From our mutational studies, we found that both the N- and C-terminal Zn-finger motifs are indispensable for the activity of LNX1, unlike LNX2, which only requires the N-terminal motif for function [24]. To our knowledge, this is the first reported case where two Zn-finger motifs are necessary for R
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These studies suggested that PV PVH might promote bone
2020-08-04
These studies suggested that PV/PVH might promote bone formation activities and/or inhibit bone resorption activities probably due to its anti-inflammation activity; however, the underlying mechanism remained unknown. Furthermore, it is unclear if PVH shows better activity than that of PV; this is i
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