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Three main transport systems are involved in
2021-10-29
Three main transport systems are involved in solute loss and red cell dehydration (summarised in Fig. 1: Lew and Bookchin, 2005): the deoxygenation-induced cation conductance (sometimes termed Psickle), the Ca-activated K+ channel (or Gardos channel) and the KCl cotransporter (KCC). Psickle is activ
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br Results and discussion br Conclusion In normal
2021-10-29
Results and discussion Conclusion In normal and curd coconuts, full-length cDNA and parental genomic DNA sequences encoding endosperm specific AGal were sequenced and characterized. At least, three mutation propionitrile were identified in CnAGal gene. In vitro expression in K. phaffii showed
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br Introduction GPR also known as free fatty acid receptor
2021-10-29
Introduction GPR40 (also known as free fatty A-71623 receptor 1), a member of the G-protein coupled receptor (GPCR) family, is expressed in pancreatic beta cells, intestine and the central nervous system (Bekinschtein et al., 2008; Itoh et al., 2003). It is activated by medium- and long-chain sa
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It is known that microglial
2021-10-29
It is known that microglial function and morphology are closely related [20], but no studies have addressed whether neuroinflammation induced by alcohol might modify microglial SR1078 mg (i.e. morphology, neuroimmunochemical phenotype) through an eCB-dependent mechanism. Since this alcohol-induced
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Endotoxin induced pulmonary hypertension is a reproducible f
2021-10-29
Endotoxin induced-pulmonary Eeyarestatin I synthesis is a reproducible finding in various animal models Leeper-Woodford et al., 1991, Weitzberg et al., 1993 and is also a feature of human sepsis where it may affect right ventricular function (Vincent, 1998). Mechanisms such as vasoconstriction and
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It has been demonstrated that
2021-10-29
It has been demonstrated that HO-1 inhibits the production of proinflammatory mediators including TNF-α and IL-6 in response to sepsis [35], and the expression of iNOS and COX-2 [36,37]. An inverse association between HO-1 and iNOS has previously been described: the NO levels decline with increases
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In conclusion these data in combination with previously desc
2021-10-28
In conclusion, these data in combination with previously described reports of GC-B being inactivated by dephosphorylation in response to other signaling molecules, strongly suggests that distinct hormonal systems inactivate GC-B by a general dephosphorylation mechanism. Identification of the modifie
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br Materials and methods br Results br
2021-10-28
Materials and methods Results Discussion and conclusions Our data demonstrate that native and 2-OMe-LPC analogues are GPR119 ligands and activate insulin secretion from βTC-3 pancreatic cells. LPC 18:1 was the first proposed endogenous ligand for GPR119 [1], however natural LPC has limited
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br Introduction Edible bird s nest EBN known
2021-10-28
Introduction Edible bird's nest (EBN), known as the health and precious food, is produced from the saliva secretion of several different swiftlet species. Researches have shown the nutritional value of the EBN with the containing of glycoproteins, carbohydrates, essential amino acids, minerals an
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Long non coding RNAs lncRNAs
2021-10-28
Long non-coding RNAs (lncRNAs) are mRNA-like transcripts of greater than 200 nucleotides (nt), with little or no protein-coding potential [13,14]. LncRNAs have been suggested to participate in transcription and post-transcription regulation as scaffolds, guides, decoys or repressors, activators, and
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molarity conversion The molecular identity of RA
2021-10-28
The molecular identity of RA’s target during LTP induction was determined by pharmacological testing. The inhibitory effects of CNQX and niflumic acid on LTP induction remained even in the presence of RA, indicating RA did not affect either the AMPA receptor nor chloride channel (Fig. 2B and D) [26]
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The presence of ghrelin s
2021-10-28
The presence of ghrelin's mRNA in the eye and the presence of ghrelin in the aqueous humor, along with a decrease of its levels in glaucoma, suggest a local role for this peptide in the ocular tissue [8], [16], [18]. There is no available data regarding the presence of GHSR-1 in the anterior segment
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Here we used chemogenetic modulation of MBH
2021-10-28
Here, we used chemogenetic modulation of MBH GHSR neurons to address the role of the endogenous ghrelin system in the normal, hyperphagic response to a short-term fast. Studies demonstrating the requirement of an intact ghrelin-GHSR system for the rebound food intake following fasting have been inco
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br Involvement of gap junctions and Panx
2021-10-28
Involvement of gap junctions and Panx1 in spinal cord processing of pain information Several studies indicated that GJs in the CNS contribute to pain. A common finding in such studies is that intrathecal administration of GJ blocker attenuates pain behavior. For example, intrathecal CBX attenuate
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KN-92 phosphate sale br Conflicts of interest br Acknowledge
2021-10-28
Conflicts of interest Acknowledgements This research was supported by grants from National Research Foundation, Korea (NRF-2017RIDIA3B04033313) and Yeungnam University (216-A-061-042). Introduction Kluyveromyces lactis is a yeast that produces one of the ß-galactosidases (ß-gals) most wide
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