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The presence of FBP in nuclei seems to accompany the
2022-06-02

The presence of FBP2 in nuclei seems to accompany the cells' potential to divide as it has been shown that during differentiation of the satellite cells (myogenic progenitor cells) the amount of nuclear FBP2 decreases and in differentiated myotubes, the localisation of FBP2 is restricted to cytoplas
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Another important question for future studies
2022-06-02

Another important question for future studies will be whether FAAH inhibitors work to normalize impairments in fear extinction that are known to be produced by environmental insults such as exposure to abused drugs and stress 97, 103. Indeed, several authors have posited utility of FAAH inhibitors f
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br Problem of cellular retention not
2022-06-02

Problem of cellular retention not only affects the cellular activity of the nanoparticles and nanocomplexes but can also have ramifications in their in vivo applications. While inorganic nanoparticles are being developed extensively for detection as well as treatment of different human diseases, i
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A small number of patients had accessory integrase mutations
2022-06-02

A small number of patients (11%) had accessory integrase mutations (E157Q, G163R, L74IM, and/or V151I) that confer potential or low-level resistance and generally only when they occur in combination with other high/intermediate level resistance mutations. This is a somewhat higher incidence than tha
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Our extensive preliminary data suggest that the loss
2022-06-02

Our extensive preliminary data suggest that the loss of p300 (and resulting H3K27ac) is related to inorganic arsenic related diseases. Therefore, it may open a new avenue for alleviating the consequence of H3K27ac, for example, via boosting CBP enzymatic activity for at least partially compensating
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Previous studies have attributed the changes
2022-06-02

Previous studies have attributed the changes that occurs during the behvioral sensitization to many psychostimulants with neuroadaptation in dopaminergic cell bodies of the VTA (induction phase) along with alteration in dopamine axon terminal field transmission of NAc during the expression to sensit
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br Conclusion Our data allow pharmacological
2022-06-02

Conclusion Our data allow pharmacological discrimination of diverse of H3 Niflumic acid receptor antagonists that can be linked to their differential efficacy in preclinical and clinical disease settings (Fig. 6). Moreover, we identify the sigma-1 receptor as a common “off target” for H3 antagon
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br Structural studies of GCAP Recoverin was the first member
2022-06-02

Structural studies of GCAP Recoverin was the first member of this subfamily of Ca2+-binding Methylprednisolone Sodium Succinate receptor to be investigated by structural methods [27], [54], [55], [56], [57], [58]. These proteins have four EF-hands arranged in pairs that give rise to amino- and c
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ceramidase br NO GC pathway and
2022-06-02

NO-GC-1 pathway and implications for glaucoma Direct in vivo measurement of NO in the eye is not yet feasible. However, measurement of nitrate and nitrite levels are routinely used as markers for the activity of NOS and the production of NO radicals [98]. Several studies in human glaucoma patient
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A few research articles described that PLGA
2022-06-02

A few research articles described that PLGA could alone improve physiological activities in certain illnesses by exerting therapeutic effects. These reported therapeutic activities of PLGA can be appended to the hydrolysis products of PLGA lactate, glycolate, and H+. We will recapitulate their respe
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br Disclosure summary br Acknowledgments br Introduction Sym
2022-06-02

Disclosure summary Acknowledgments Introduction Symbionts are live microorganisms that seem to promote host defense systems and regulate intestinal homeostasis, preventing gut infectious and inflammatory diseases (Fuller, 1989, Sartor, 2004). Numerous studies have shown the beneficial effec
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We hypothesized that modulating redox stress
2022-06-02

We hypothesized that modulating redox stress by altering endogenous antioxidant content (overexpression of catalase) and/or via dietary intervention will improve energy metabolism, adipose tissue function, and overall glucose and lipid homeostasis. To better understand the interplay between redox re
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Dendritic damage and loss of synaptic connections correlate
2022-06-02

Dendritic damage and loss of synaptic connections correlate with cognitive decline in HAND patients. Synapse loss induced by HIV proteins occurs early and via a different signaling pathway from that leading to neuronal death (Kim et al., 2008), suggesting that synapse loss might be a mechanism to re
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Pregnancy per AI results at days post
2022-06-02

Pregnancy per AI results at 32 days post TAI tended to differ among GnRH products and was greater for FER and CYS than FAC according to the Tukey-grouping analysis statistical approach (Table 1). In addition, P/AI was greater for cows treated with gonadorelin diacetate products than for cows treated
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Enzyme linked immunosorbent assay ELISA is a rapid and simpl
2022-06-01

Enzyme-linked immunosorbent assay (ELISA) is a rapid and simple test widely used for the detection of humoral immune responses following infection/vaccination. However, commercially available ILTV ELISA use the whole virus as the detecting antigen and therefore may not be sensitive for the detection
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